![](/StructureFile/ChemBookStructure22/GIF/CB8957359.gif)
5'-Bromo-2',6-difluorobiphenyl-2-carbonitrile synthesis
- Product Name:5'-Bromo-2',6-difluorobiphenyl-2-carbonitrile
- CAS Number:425379-21-1
- Molecular formula:C13H6BrF2N
- Molecular Weight:294.09
Yield:425379-21-1 30%
Reaction Conditions:
Stage #1: 2,4-dibromo-1-fluorobenzenewith isopropylmagnesium chloride
Stage #2:
Stage #3: 2-bromo-3-fluorobenzonitrile;tris(dibenzylideneacetone)dipalladium (0);tri-tert-butyl phosphine in tetrahydrofuran at 23; for 1 h;
References:
Gauthier Jr., Donald R.;Limanto, John;Devine, Paul N.;Desmond, Richard A.;Szumigala Jr., Ronald H.;Foster, Bruce S.;Volante [Journal of Organic Chemistry,2005,vol. 70,# 15,p. 5938 - 5945]
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![3-Fluorobenzonitrile](/CAS/GIF/403-54-3.gif)
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$7.00/5g
![5'-Bromo-2',6-difluorobiphenyl-2-carbonitrile](/StructureFile/ChemBookStructure22/GIF/CB8957359.gif)
425379-21-1
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