5-BROMO-2-FLUOROBENZAMIDE synthesis
- Product Name:5-BROMO-2-FLUOROBENZAMIDE
- CAS Number:214210-17-0
- Molecular formula:C7H5BrFNO
- Molecular Weight:218.02
179897-89-3
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$10.00/5g
214210-17-0
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$60.00/50mg
Yield:-
Reaction Conditions:
in sulfuric acid
Steps:
82.a a
a 2-Fluoro-5-bromobenzamide 5-Bromo-2-fluorobenzonitrile (0.370 g) was heated at 110° C. for 1 hour in concentrated sulfuric acid (10 ml). After cooling, the reaction was diluted with ice-cold water and the slurry was extracted into ethyl acetate, dried over anhydrous magnesium sulfate, filtered and evaporated to afford the sub-title compound as a solid (0.328 g). 1H NMR (CDCl3) 8.26 (1H, m); 7.61 (1H, m); 7.05 (1H, m); 6.64 (1H, bs); 5.89 (1H, br.s).
References:
AstraZeneca AB US6300352, 2001, B1
773140-42-4
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214210-17-0
36 suppliers
$60.00/50mg
146328-85-0
282 suppliers
$6.00/1g
214210-17-0
36 suppliers
$60.00/50mg