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5-Bromo-2-methoxy-3-pyridinamine hydrochloride synthesis

3synthesis methods
67443-38-3 Synthesis
5-Bromo-2-chloro-3-nitropyridine

67443-38-3
364 suppliers
$5.00/1g

5-Bromo-2-methoxy-3-pyridinamine hydrochloride

1361970-57-1
3 suppliers
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Yield:1361970-57-1 18.1 kg

Reaction Conditions:

Stage #1: 5-bromo-2-chloro-3-nitropyridine;sodium methylate in methanol; for 1 h;Large scale;
Stage #2: with hydrogenchloride;iron in methanol;water at 40;Large scale;

References:

Edney, Dean;Hulcoop, David G.;Leahy, John H.;Vernon, Lois E.;Wipperman, Mark D.;Bream, Robert N.;Webb, Michael R. [Organic Process Research and Development,2018,vol. 22,# 3,p. 368 - 376]

152684-30-5 Synthesis
5-BROMO-2-METHOXY-3-NITRO-PYRIDINE

152684-30-5
217 suppliers
$6.00/1g

5-Bromo-2-methoxy-3-pyridinamine hydrochloride

1361970-57-1
3 suppliers
inquiry

67443-38-3 Synthesis
5-Bromo-2-chloro-3-nitropyridine

67443-38-3
364 suppliers
$5.00/1g

5-Bromo-2-methoxy-3-pyridinamine hydrochloride

1361970-57-1
3 suppliers
inquiry