5-Chloro-2-Methyl-3-phenyl-1H-indole synthesis

5synthesis methods

Product Name:5-Chloro-2-Methyl-3-phenyl-1H-indole
CAS Number:30843-37-9
Molecular formula:C15H12ClN
Molecular Weight:241.72

5922-60-1 Synthesis

5922-60-1
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Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: palladium(II) trifluoroacetate; methanesulfonic acid; [2,2]bipyridinyl / tetrahydrofuran; water / 36 h / 80 °C
2.1: potassium tert-butylate / tetrahydrofuran / 20 °C / Inert atmosphere
2.2: 5 h / 50 °C / Inert atmosphere
3.1: dipotassium peroxodisulfate; iron(II) fluoride; triethylamine / tetrahydrofuran / 16 h / 70 °C

References:

Li, Yudong;Li, Yuehui;Luo, Shuping;Wang, Menglan;Wu, Qing-An [Synthesis,2019,vol. 51,# 16,p. 3085 - 3090]

673-32-5 Synthesis