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ChemicalBook CAS DataBase List 5-CHLOROBENZO-2,1,3-THIADIAZOLE

5-CHLOROBENZO-2,1,3-THIADIAZOLE synthesis

3synthesis methods
5-Chlorobenzo-2,1,3-thiadiazole can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly  in laboratory research. It can be synthesized by ring closure reaction of 4-Chloro-o-phenylenediamine with thionyl chloride in chloroform.
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Yield: 89.1%

Reaction Conditions:

with pyridine;thionyl chloride in chloroform for 5 h;

References:

Mo, Daize;Wang, Huan;Chen, Hui;Qu, Shiwei;Chao, Pengjie;Yang, Zhen;Tian, Leilei;Su, Yu-An;Gao, Yu;Yang, Bing;Chen, Wei;He, Feng [Chemistry of Materials,2017,vol. 29,# 7,p. 2819 - 2830]

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