![](/CAS/GIF/305832-67-1.gif)
5-Cyanothiophene-2-boronic acid synthesis
- Product Name:5-Cyanothiophene-2-boronic acid
- CAS Number:305832-67-1
- Molecular formula:C5H4BNO2S
- Molecular Weight:152.97
![2-Thiophenecarbonitrile](/CAS/GIF/1003-31-2.gif)
1003-31-2
299 suppliers
$6.00/5g
![5-Cyanothiophene-2-boronic acid](/CAS/GIF/305832-67-1.gif)
305832-67-1
157 suppliers
$8.00/250mg
Yield: 89%
Reaction Conditions:
Stage #1:thiophene-2-carbonitrile with Triisopropyl borate;lithium hexamethyldisilazane in tetrahydrofuran at -78; for 0.5 h;Nitrogen atmosphere;
Stage #2: with hydrogenchloride in tetrahydrofuran;water
References:
American Home Products Corporation;Ligand Pharmaceuticals, Inc. US6355648, 2002, B1 Location in patent:Page column 64