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ChemicalBook CAS DataBase List 5α-Estrane-3β,17β-diol
1816-75-7

5α-Estrane-3β,17β-diol synthesis

4synthesis methods
-

Yield:56 % de

Reaction Conditions:

with chloro{[(1S,2S)-(+)-2-amino-1,2-diphenylethyl](4-toluenesulfonyl)amido}(p-cymene)ruthenium(II);potassium hydroxide in isopropyl alcohol at 20; for 2 h;Inert atmosphere;diastereoselective reaction;Noyori Asymmetric Hydrogenation;

References:

Balssa, Frédéric;Fischer, Michael;Bonnaire, Yves [Steroids,2014,vol. 86,p. 1 - 4]