![](/CAS/GIF/875305-87-6.gif)
5-fluoro-1H-indole-7-carboxylic acid synthesis
- Product Name:5-fluoro-1H-indole-7-carboxylic acid
- CAS Number:875305-87-6
- Molecular formula:C9H6FNO2
- Molecular Weight:179.15
![Carbon dioxide](/CAS/GIF/124-38-9.gif)
124-38-9
121 suppliers
$214.00/14L
![7-BROMO-5-FLUOROINDOLE](/CAS/GIF/408355-23-7.gif)
408355-23-7
80 suppliers
$54.00/250mg
![5-fluoro-1H-indole-7-carboxylic acid](/CAS/GIF/875305-87-6.gif)
875305-87-6
24 suppliers
$495.50/5MG
Yield:875305-87-6 54%
Reaction Conditions:
Stage #1: 7-bromo-5-fluoro-1H-indolewith sec.-butyllithium in tetrahydrofuran;cyclohexane at -75;
Stage #2: carbon dioxide in tetrahydrofuran;cyclohexane;cooling;
References:
Schlosser, Manfred;Ginanneschi, Assunta;Leroux, Frederic [European Journal of Organic Chemistry,2006,# 13,p. 2956 - 2969]
![3-Bromofluorobenzene](/CAS/GIF/1073-06-9.gif)
1073-06-9
432 suppliers
$6.00/10g
![5-fluoro-1H-indole-7-carboxylic acid](/CAS/GIF/875305-87-6.gif)
875305-87-6
24 suppliers
$495.50/5MG
![2-Bromo-4-fluoronitrobenzene](/CAS/GIF/700-36-7.gif)
700-36-7
204 suppliers
$10.00/1g
![5-fluoro-1H-indole-7-carboxylic acid](/CAS/GIF/875305-87-6.gif)
875305-87-6
24 suppliers
$495.50/5MG