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5-Iodo-pyrimidine-2,4-diamine synthesis

1synthesis methods
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Yield:157924-46-4 97%

Reaction Conditions:

Stage #1: pyrimidine-2,4-diaminewith periodic acid;sulfuric acid;iodine;acetic acid in water monomer; for 5.5 h;
Stage #2: with potassium hydroxide in water monomer at 20;

References:

Wellington, Kevin W.;Ooi, Hua Chee;Benner, Steven A. [Nucleosides, nucleotides and nucleic acids,2009,vol. 28,# 4,p. 275 - 291] Location in patent:experimental part