![](/CAS/20180703/GIF/1144854-04-5.gif)
5-Iodobenzofuran-2-carboxylic acid synthesis
- Product Name:5-Iodobenzofuran-2-carboxylic acid
- CAS Number:1144854-04-5
- Molecular formula:C9H5IO3
- Molecular Weight:288.04
![5-Iodo-benzofuran-2-carboxylic acid ethyl ester](/CAS2/GIF/929193-49-7.gif)
929193-49-7
6 suppliers
inquiry
![5-Iodobenzofuran-2-carboxylic acid](/CAS/20180703/GIF/1144854-04-5.gif)
1144854-04-5
11 suppliers
inquiry
Yield:1144854-04-5 66%
Reaction Conditions:
Stage #1: 5-iodobenzofuran-2-carboxylic acid ethyl esterwith potassium hydroxide in ethanol;water; for 1 h;Reflux;
Stage #2: with hydrogenchloride in water; pH=2 - 3;Heating;
References:
Newman, Amy Hauck;Grundt, Peter;Cyriac, George;Deschamps, Jeffrey R.;Taylor, Michelle;Kumar, Rakesh;Ho, David;Luedtke, Robert R. [Journal of Medicinal Chemistry,2009,vol. 52,# 8,p. 2559 - 2570] Location in patent:experimental part