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(5-Methoxy-2-(phenylethynyl)phenyl)methanol synthesis

6synthesis methods
Benzenemethanol, 2-iodo-5-methoxy-

139557-96-3
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(5-Methoxy-2-(phenylethynyl)phenyl)methanol

1205555-48-1
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Yield:1205555-48-1 92%

Reaction Conditions:

with copper(l) iodide;tetrakis(triphenylphosphine) palladium(0);triethylamine in tetrahydrofuran at 20; for 24 h;Inert atmosphere;Sonogashira Cross-Coupling;

References:

Hessler, Filip;Betk, Robert;Kadlkov, Aneta;Belle, Roman;Kotora, Martin [European Journal of Organic Chemistry,2014,vol. 2014,# 32,p. 7245 - 7252] Location in patent:supporting information