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5-(p-ethoxyphenyl)-5-methyl-hydantoi synthesis

1synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: aluminum (III) chloride; carbonic acid dimethyl ester / 20 °C
2: water; ethanol / 70 °C

References:

Koura, Minoru;Matsuda, Takayuki;Okuda, Ayumu;Watanabe, Yuichiro;Yamaguchi, Yuki;Kurobuchi, Sayaka;Matsumoto, Yuuki;Shibuya, Kimiyuki [Bioorganic and Medicinal Chemistry Letters,2015,vol. 25,# 13,p. 2668 - 2674]