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(5-P-TOLYL-TETRAZOL-2-YL)-ACETIC ACID synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: sodium ethanolate / ethanol
2: sodium hydroxide / tetrahydrofuran; water

References:

Sharma, Swagat;Kozek, Krystian A.;Abney, Kristopher K.;Kumar, Sushil;Gautam, Nagsen;Alnouti, Yazen;David Weaver;Hopkins, Corey R. [Bioorganic and Medicinal Chemistry Letters,2019,vol. 29,# 6,p. 791 - 796]