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5-Phenyl-3-thiophenecarboxaldehyde synthesis

4synthesis methods
3-Thiophenecarboxamide, N-methoxy-N-methyl-5-phenyl-

1311195-94-4
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Yield:38115-12-7 84.8%

Reaction Conditions:

with lithium aluminium tetrahydride in tetrahydrofuran at -78 - -20; for 1 h;Inert atmosphere;

References:

Lu, Yan;Li, Chien-Ming;Wang, Zhao;Chen, Jianjun;Mohler, Michael L.;Li, Wei;Dalton, James T.;Miller, Duane D. [Journal of Medicinal Chemistry,2011,vol. 54,# 13,p. 4678 - 4693] Location in patent:supporting information; experimental part

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