ChemicalBook CAS DataBase List 5-PHENYL-O-ANISIDINE

5-PHENYL-O-ANISIDINE synthesis

13synthesis methods

Product Name:5-PHENYL-O-ANISIDINE
CAS Number:39811-17-1
Molecular formula:C13H13NO
Molecular Weight:199.25

15854-73-6
46 suppliers
$25.00/1 g

39811-17-1
83 suppliers
$37.89/1g

Yield: 99%

Reaction Conditions:

with palladium 10% on activated carbon;hydrogen in methanol for 8 h;

Steps:

1
Compound II-3 (669 mg, 2.91 mmol)Soluble in methanol (9.7mL, 0.3M),Add 10% Pd/C (67 mg),After reacting for 8 hours under hydrogen pressure,TLC monitoring showed the end of the reaction.Diatomaceous earth suction filtration,The filtrate was dried under reduced pressure to give compound II-4(Brown solid, 575 mg, yield 99%).

References:

China Pharmaceutical University;Yan Dingfei;Cheng Yalong;Sun Hongbin CN109293537, 2019, A Location in patent:Paragraph 0044; 0046; 0049