5-(TRIFLUOROMETHOXY)INDOLIN-2-ONE synthesis
- Product Name:5-(TRIFLUOROMETHOXY)INDOLIN-2-ONE
- CAS Number:403853-48-5
- Molecular formula:C9H6F3NO2
- Molecular Weight:217.14
169037-23-4
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403853-48-5
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Yield:403853-48-5 93%
Reaction Conditions:
Stage #1: 5-trifluoromethoxy-1H-indole-2,3-dionewith hydrazine hydrate at 140; for 4 h;
Stage #2: with hydrogenchloride;water at 20; pH=2; for 48 h;
References:
Mologni, Luca;Rostagno, Roberta;Brussolo, Stefania;Knowles, Phillip P.;Kjaer, Svend;Murray-Rust, Judith;Rosso, Enrico;Zambon, Alfonso;Scapozza, Leonardo;McDonald, Neil Q.;Lucchini, Vittorio;Gambacorti-Passerini, Carlo [Bioorganic and Medicinal Chemistry,2010,vol. 18,# 4,p. 1482 - 1496] Location in patent:experimental part
461-82-5
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403853-48-5
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$45.00/50mg
1416818-65-9
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403853-48-5
38 suppliers
$45.00/50mg