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5-(TRIFLUOROMETHYL)PIPERIDIN-2-ONE synthesis

2synthesis methods
33252-63-0 Synthesis
2-Hydroxy-5-trifluoromethylpyridine

33252-63-0
286 suppliers
$10.00/1g

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Yield:50549-24-1 89%

Reaction Conditions:

with platinum(IV) oxide;hydrogen in trifluoroacetic acid at 20; under 760.051 Torr;

References:

Alekseenko, Anatoliy N.;Bugera, Maksym Ya.;Gerus, Igor I.;Kiriakov, Oleksandr;Klipkov, Anton A.;Mykhailiuk, Pavel K.;Pustovit, Yurii;Razhyk, Bohdan;Semenov, Sergey;Starova, Viktoriia S.;Tananaiko, Oksana Yu.;Tarasenko, Karen;Tolmachev, Andrei A.;Trofymchuk, Serhii;Zaporozhets, Olga A. [Journal of Organic Chemistry,2020,vol. 85,# 5,p. 3110 - 3124]