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3-Amino-5-nitrothieno[2,3-b]pyridine-2-carboxylic acid ethyl ester synthesis

2synthesis methods
-

Yield:52505-43-8 97.8%

Reaction Conditions:

with sodium ethanolate in ethanol;Heating;Thorpe-Ziegler cyclization;

References:

Yakovlev;Kadushkin;Granik [Pharmaceutical Chemistry Journal,1996,vol. 30,# 2,p. 107 - 109]