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ChemicalBook CAS DataBase List (2S)-5-amino-2-(tert-butoxycarbonylamino)-pentanoic acid tert-butyl ester
53054-03-8

(2S)-5-amino-2-(tert-butoxycarbonylamino)-pentanoic acid tert-butyl ester synthesis

7synthesis methods
24424-99-5 Synthesis
Di-tert-butyl dicarbonate

24424-99-5
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(2S)-5-amino-2-(tert-butoxycarbonylamino)-pentanoic acid tert-butyl ester

53054-03-8
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: 95 percent / satd. NaHCO3 / dioxane; H2O / 13 h / Ambient temperature
2: 85 percent / H2 / Pd/C / methanol

References:

Clement;Schnoerwangen;Kaempchen;Mordvintcev;Muelsch [Archiv der Pharmazie,1994,vol. 327,# 12,p. 793 - 798]