![](/CAS/GIF/53439-88-6.gif)
5-AMINO-1,3-DIMETHYL-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE synthesis
- Product Name:5-AMINO-1,3-DIMETHYL-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE
- CAS Number:53439-88-6
- Molecular formula:C9H11N3O
- Molecular Weight:177.2
![1,3-Dimethyl-5-nitro-1H-benzo[d]imidazol-2(3H)-one](/CAS/GIF/43027-50-5.gif)
43027-50-5
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![5-AMINO-1,3-DIMETHYL-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE](/CAS/GIF/53439-88-6.gif)
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Yield: 100%
Reaction Conditions:
with hydrogenchloride;hydrogen;palladium 10% on activated carbon in ethanol;water
Steps:
3
1.4 g of 1,3-dimethyl-5-nitro-1H-benzo[d]imidazol-2(3H)-one was suspended in 100 mL EtOH and 100 uL conc. HCl and 2 scoops of 10% Pd/C was added and an H2 balloon was attached and stirred overnight. The solution was then filtered through celite and concentrated in vacuo to give 1.27 g of the amine 5-amino-1,3-dimethyl-1H-benzo[d]imidazol-2(3H)-one (106% yield).
References:
Rawson, Thomas E.;Safina, Brian;Dotson, Jennafer;Zhou, Aihe;Aliagas-Martin, Ignacio;Halladay, Jason;Liang, Jun;Rueth, Matthias;Zhu, Bing-Yan US2007/37791, 2007, A1 Location in patent:Page/Page column 41
![1,3-DIMETHYL-2-OXO-2,3-DIHYDRO-1 H-BENZOIMIDAZOLE-5-CARBOXYLIC ACID](/StructureFile/ChemBookStructure6/GIF/CB8287496.gif)
64826-45-5
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$45.00/10mg
![5-AMINO-1,3-DIMETHYL-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE](/CAS/GIF/53439-88-6.gif)
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![1,3-Dimethyl-2-oxo-2,3-dihydro-1H-benzoimidazole-5-carboxylic acid methyl ester](/CAS/20180629/GIF/222424-21-7.gif)
222424-21-7
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![5-AMINO-1,3-DIMETHYL-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE](/CAS/GIF/53439-88-6.gif)
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![5-NITRO-2-BENZIMIDAZOLINONE](/CAS/GIF/93-84-5.gif)
93-84-5
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$20.39/1g
![5-AMINO-1,3-DIMETHYL-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE](/CAS/GIF/53439-88-6.gif)
53439-88-6
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