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ChemicalBook CAS DataBase List Pentacyclo[4.2.0.02,5.03,8.04,7]octanecarboxylic acid (7CI,9CI)

Pentacyclo[4.2.0.02,5.03,8.04,7]octanecarboxylic acid (7CI,9CI) synthesis

9synthesis methods
-

Yield:53578-15-7 99%

Reaction Conditions:

Stage #1: monocarbomethoxycubanewith sodium hydroxide in tetrahydrofuran;methanol at 20; for 12 h;
Stage #2: with hydrogenchloride in water; pH=Ca. 3;

References:

Wlochal, Joanna;Davies, Robert D. M.;Burton, Jonathan [Organic Letters,2014,vol. 16,# 16,p. 4094 - 4097] Location in patent:supporting information

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