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ChemicalBook CAS DataBase List (AS)-ALPHA-AMINO-3-[(4-CARBOXYPHENYL)METHYL]-3,4-DIHYDRO-2,4-DIOXO-1(2H)-PYRIMIDINEPROPANOIC ACID
544697-47-4

(AS)-ALPHA-AMINO-3-[(4-CARBOXYPHENYL)METHYL]-3,4-DIHYDRO-2,4-DIOXO-1(2H)-PYRIMIDINEPROPANOIC ACID synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: NaH / dimethylformamide / 2 h / 20 °C
1.2: dimethylformamide / 48 h / 20 °C
2.1: 20 percent / aq. HCl / 2 h / Heating

References:

Dolman, Nigel P.;Troop, Helen M.;More, Julia C. A.;Alt, Andrew;Knauss, Jody L.;Nistico, Robert;Jack, Samantha;Morley, Richard M.;Bortolotto, Zuner A.;Roberts, Peter J.;Bleakman, David;Collingridge, Graham L.;Jane, David E. [Journal of Medicinal Chemistry,2005,vol. 48,# 24,p. 7867 - 7881]

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