ChemicalBook CAS DataBase List 7-broMo-2-(3-fluoro-4-hydroxyphenyl)-1,3-benzoxazol-5-ol

7-broMo-2-(3-fluoro-4-hydroxyphenyl)-1,3-benzoxazol-5-ol synthesis

7synthesis methods

Product Name:7-broMo-2-(3-fluoro-4-hydroxyphenyl)-1,3-benzoxazol-5-ol
CAS Number:544704-73-6
Molecular formula:C13H7BrFNO3
Molecular Weight:324.1

7-broMo-2-(3-fluoro-4-Methoxyphenyl)-5-Methoxy-1,3-benzoxazole

544704-75-8
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7-broMo-2-(3-fluoro-4-hydroxyphenyl)-1,3-benzoxazol-5-ol

544704-73-6
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Yield:544704-73-6 93%

Reaction Conditions:

with boron tribromide in dichloromethane at -78 - 20;

References:

Malamas, Michael S.;Manas, Eric S.;McDevitt, Robert E.;Gunawan, Iwan;Xu, Zhang B.;Collini, Michael D.;Miller, Chris P.;Dinh, Tam;Henderson, Ruth A.;Keith Jr., James C.;Harris, Heather A. [Journal of Medicinal Chemistry,2004,vol. 47,# 21,p. 5021 - 5040]