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4-HYDROXYTHIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID ETHYL ESTER synthesis

2synthesis methods
-

Yield:55503-31-6 75%

Reaction Conditions:

in diphenylether; for 0.166667 h;Heating;Gould-Jacob cyclization;

References:

Schnute, Mark E.;Cudahy, Michele M.;Brideau, Roger J.;Homa, Fred L.;Hopkins, Todd A.;Knechtel, Mary L.;Oien, Nancee L.;Pitts, Thomas W.;Poorman, Roger A.;Wathen, Michael W.;Wieber, Janet L. [Journal of Medicinal Chemistry,2005,vol. 48,# 18,p. 5794 - 5804]