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6-Methyl-4-(trifluoromethyl)-2,3-dihydropyridazin-3-one synthesis

3synthesis methods
Pentanethioic acid, 4-oxo-2-(trifluoromethyl)-, S-ethyl ester

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6-Methyl-4-(trifluoromethyl)-2,3-dihydropyridazin-3-one

560132-48-1
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: 75 percent / PTSA; N2H4 / toluene / 5 h / Heating
2: 81 percent / CuCl2 / acetonitrile / 7 h / Heating

References:

Brule, Cedric;Bouillon, Jean-Philippe;Nicolai, Eric;Portella, Charles [Synthesis,2003,# 3,p. 436 - 442]