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5-fluoro-1,3-dihydro-1-(4-piperidinyl)-2H-benziMidazol-2-one synthesis

9synthesis methods
4-(5-fluoro-2-oxo-2,3-dihydro-benzoiMidazol-1-yl)-piperidine-1-carboxylic acid ethyl ester

107618-33-7
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Yield:58859-77-1 88%

Reaction Conditions:

with sodium hydroxide for 8 h;Heating;

References:

Henning;Lattrell;Gerhards;Leven [Journal of Medicinal Chemistry,1987,vol. 30,# 5,p. 814 - 820]