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(2R)-2-(4-Hydroxyphenyl)propionic acid, (R)-(4-Hydroxyphenyl)(methyl)acetic acid, 4-[(1R)-1-Carboxyethyl]phenol
(2R)-2-(4-Hydroxyphenyl)propionic acid, (R)-(4-Hydroxyphenyl)(methyl)acetic acid, 4-[(1R)-1-Carboxyethyl]phenol synthesis
2synthesis methods
- Product Name:(2R)-2-(4-Hydroxyphenyl)propionic acid, (R)-(4-Hydroxyphenyl)(methyl)acetic acid, 4-[(1R)-1-Carboxyethyl]phenol
- CAS Number:59092-88-5
- Molecular formula:C9H10O3
- Molecular Weight:166.17
Yield:98 % ee
Reaction Conditions:
with lipase from Candida rugosa in aq. phosphate buffer at 45; pH=6.5; for 24 h;Resolution of racemate;Optical yield = 85 %ee; enantioselective reaction;Reagent/catalyst;
References:
Yuan, Xin;Zhang, Panliang;Liu, Guangyong;Xu, Weifeng;Tang, Kewen [Chemical Papers,2019,vol. 73,# 10,p. 2461 - 2468]
