D-Iditol, 1,6-dideoxy-1,6-epithio-3,4-O-(1-methylethylidene)- (9CI) synthesis

Yield:-

Steps:

Multi-step reaction with 2 steps
1: m-CPBA; 5-tert-butyl-4-hydroxy-2-methylphenyl sulfide / 1,2-dichloro-ethane / 3 h / 90 °C
2: Na₂S*9H₂O / ethanol / 48 h / Heating

References:

Cere, Vanda;Peri, Francesca;Pollicino, Salvatore;Ricci, Alfredo;Devlin, Frank J.;Stephens, Philip J.;Gasparrini, Francesco;Rompietti, Romina;Villani, Claudio [Journal of Organic Chemistry,2005,vol. 70,# 2,p. 664 - 669]

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