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63328-12-1

(5R)-5-1-Methylethyl-2-Pyrrolidinone synthesis

3synthesis methods
(R)-N-t-butoxycarbonyl-5-isopropyl-2-pyrrolidinone

147778-56-1
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(5R)-5-1-Methylethyl-2-Pyrrolidinone

63328-12-1
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Yield:63328-12-1 94%

Reaction Conditions:

with trifluoroacetic acid in dichloromethane at 20; for 1 h;

References:

Thomas, Eric J.;Willis, Mark [Organic and biomolecular chemistry,2014,vol. 12,# 38,p. 7537 - 7550] Location in patent:supporting information