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6-(2-FURYL)NICOTINONITRILE synthesis

2synthesis methods
-

Yield:619334-28-0 80.6%

Reaction Conditions:

with tetrakis(triphenylphosphine) palladium(0) in 1,4-dioxane at 100 - 110; for 24 h;Stille coupling;

References:

Ismail, Mohamed A.;Brun, Reto;Easterbrook, Judy D.;Tanious, Farial A.;Wilson, W. David;Boykin, David W. [Journal of Medicinal Chemistry,2003,vol. 46,# 22,p. 4761 - 4769]