6,6-dimethylmorpholin-3-one synthesis

2synthesis methods

Product Name:6,6-dimethylmorpholin-3-one
CAS Number:1312457-13-8
Molecular formula:C6H11NO2
Molecular Weight:129.16

Acetic acid, 2-[2-[bis(phenylmethyl)amino]-1,1-dimethylethoxy]-, ethyl ester

1338493-69-8
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1312457-13-8
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Yield:1312457-13-8 100%

Reaction Conditions:

with hydrogen;palladium(II) hydroxide in ethanol at 60; for 16 h;

Steps:

172.2

(2-Dibenzylamino-l,l-dimethyl-ethoxy)-acetic acid ethyl ester (Example 172, step 1) was hydrogenated in EtOH with Pd(OH)₂ for 16 hours at 60°C. The desired 6,6-dimethyl-morpholin- 3-one (585mg, 60% purity, quant.) was obtained as a colorless liquid, MS: m/e = 129 (M+H⁺) and used in the next step without further purification

References:

WO2011/128279,2011,A1 Location in patent:Page/Page column 168

2854-16-2 Synthesis

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79-04-9 Synthesis

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1312457-13-8
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$353.00/1g

References