6,8-DibroMo-3-acetylcouMarin synthesis
- Product Name:6,8-DibroMo-3-acetylcouMarin
- CAS Number:2199-92-0
- Molecular formula:C11H6Br2O3
- Molecular Weight:345.97
Yield:2199-92-0 81%
Reaction Conditions:
with diethylamine at 20;
Steps:
Synthesis of 3-acetylcoumarin derivatives 1a-1h
General procedure: A round-bottom flask equipped with a magnetic stirrer wascharged with salicylaldehyde derivative (10 mmol), ethylacetoacetate(10 mmol), and diethylamine (10% w/w). Afterthe solid formation, the mixture was washed with dilute HClto neutralization of waste of base then ethanol was added.Synthesized 3-acetylcoumarin derivative was crystallized from ethanol. The product was identified using FT-IR andNMR spectroscopy.
References:
Er?at?r, Mehmet;Giray, Elife Sultan;Y?ld?r?m, Metin;Yal?n, Serap [Monatshefte fur Chemie,2020,vol. 151,# 4,p. 625 - 636]
