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99584-10-8

6-Amino-3-methyl-1,3-benzoxazol-2(3H)-one, 90% synthesis

6synthesis methods
-

Yield:99584-10-8 96%

Reaction Conditions:

Stage #1: 3-methyl-6-nitro-2(3H)-benzoxazolonewith hydrogenchloride;tin(ll) chloride in ethanol;water; for 1.5 h;Reflux;
Stage #2: with sodium hydroxide in ethanol;water;

References:

Guelkok, Yildiz;Bicer, Tuba;Onurdag, Fatma Kaynak;Oezgen, Selda;Sahin, Mustafa Fethi;Dogruer, Deniz Songuel [Turkish Journal of Chemistry,2012,vol. 36,# 2,p. 279 - 291] Location in patent:experimental part