6-(AMINOMETHYL)-2-PYRIDINEMETHANOL synthesis
- Product Name:6-(AMINOMETHYL)-2-PYRIDINEMETHANOL
- CAS Number:50501-31-0
- Molecular formula:C7H10N2O
- Molecular Weight:138.17
![1H-Isoindole-1,3(2H)-dione, 2-[[6-(hydroxymethyl)-2-pyridinyl]methyl]-](/CAS/20210305/GIF/154696-52-3.gif)
154696-52-3
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50501-31-0
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Yield:50501-31-0 100%
Reaction Conditions:
with hydrazine hydrate in ethanol; for 4 h;Reflux;
Steps:
[6-(Aminomethyl)-2-pyridyl]methanol (16b)
General procedure: To a solution of 1.75 g (6.5 mmol) of compound 15b in 100 mL of ethanol was added 0.325 g (6.5 mmol) of hydrazine hydrate. The mixture was boiled for 4 h and then cooled to room temperature. The precipitate was filtered off, the filtrate was evaporated to dryness to yield 0.9 g (100%) of compound 16b, which was used in the next step without further purification. Mass spectrum, m/z (Irel, %): 139.1 (100) [M + H]+.
References:
Vasilevich;Aksenova;Aksenova;Afanasyev [Russian Journal of General Chemistry,2017,vol. 87,# 4,p. 717 - 730][Zh. Obshch. Khim.,2017,vol. 87,# 4,p. 584 - 596,13]
1195-59-1
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$6.00/1g
50501-31-0
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40054-01-1
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$66.00/100mg
50501-31-0
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1122-71-0
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$9.00/1g
50501-31-0
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