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ChemicalBook CAS DataBase List 6-Chloro-2-oxoindoline-5-carboxylic acid
1156390-49-6

6-Chloro-2-oxoindoline-5-carboxylic acid synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: aluminum (III) chloride / 1,2-dichloro-ethane / 4 h / 20 °C
2.1: pyridine / 3 h / 90 °C
2.2: 3 h / 100 °C

References:

Guo, Jing;Zhu, Mingyue;Wu, Tianxiao;Hao, Chenzhou;Wang, Kai;Yan, Zizheng;Huang, Wanxu;Wang, Jian;Zhao, Dongmei;Cheng, Maosheng [Bioorganic and Medicinal Chemistry,2017,vol. 25,# 13,p. 3500 - 3511]