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6-Chloro-4-oxo-chroman-2-carboxylic acid synthesis

1synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: Aluminum Chloride / 1,2-dichloro-ethane / 0.25 h / 50 °C
1.2: 1 h / 50 °C
2.1: lithium hydroxide monohydrate; sodium hydroxide / 1 h / 100 °C

References:

WO2022/120048,2022,A1