![](/CAS/GIF/4224-62-8.gif)
6-CHLORO-N-HEXANOIC ACID synthesis
- Product Name:6-CHLORO-N-HEXANOIC ACID
- CAS Number:4224-62-8
- Molecular formula:C6H11ClO2
- Molecular Weight:150.6
![6-CHLOROHEXANAL](/CAS/GIF/52387-36-7.gif)
52387-36-7
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![6-CHLORO-N-HEXANOIC ACID](/CAS/GIF/4224-62-8.gif)
4224-62-8
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$14.00/1g
Yield:4224-62-8 81%
Reaction Conditions:
with N-hydroxyphthalimide;oxygen in acetonitrile at 30; for 3 h;Schlenk technique;
Steps:
13 Synthesis of 6-chlorohexanoic acid
15 mol% NHPI was added to a 25 mL Schlenk reaction tube, dried under vacuum for 15 minutes, oxygen was bubbled in, and 2 mL of acetonitrile and 1.0 equivalent of 6-chlorohexanal were added in an oxygen atmosphere, and an oxygen balloon was attached thereto, and a glass stopper was added to the reaction tube. After that, it was placed in an oil bath and reacted at 30 ° C for 3 h. After the completion of the reaction, the mixture was concentrated under reduced pressure and purified by column chromatography, eluting with petroleum ether / ethyl acetate / methylene chloride (v: v: v = 5:1:1) to give 6-chlorohexanoic acid. Yield 81%,Colorless liquid
References:
University of Science and Technology of China;Kang Yanbiao;Dai Pengfei CN108314599, 2018, A Location in patent:Paragraph 0041-0043
![6-Chlorohexanol](/CAS/GIF/2009-83-8.gif)
2009-83-8
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$7.00/25g
![6-CHLORO-N-HEXANOIC ACID](/CAS/GIF/4224-62-8.gif)
4224-62-8
121 suppliers
$14.00/1g
![1-CHLORO-5-IODOPENTANE](/CAS/GIF/60274-60-4.gif)
60274-60-4
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$31.00/5 g
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124-38-9
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![6-CHLORO-N-HEXANOIC ACID](/CAS/GIF/4224-62-8.gif)
4224-62-8
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$14.00/1g
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502-44-3
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$5.00/25g
![6-CHLORO-N-HEXANOIC ACID](/CAS/GIF/4224-62-8.gif)
4224-62-8
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![6-CHLORO-1-HEXYNE](/CAS/GIF/10297-06-0.gif)
10297-06-0
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$22.00/1 g
![6-CHLORO-N-HEXANOIC ACID](/CAS/GIF/4224-62-8.gif)
4224-62-8
121 suppliers
$14.00/1g