6-((di-tert-butylphosphino)methyl)-2,2'-bipyridine synthesis
3synthesis methods
- Product Name:6-((di-tert-butylphosphino)methyl)-2,2'-bipyridine
- CAS Number:1256651-63-4
- Molecular formula:C19H27N2P
- Molecular Weight:314.4048
Yield:1256651-63-4 85%
Reaction Conditions:
Stage #1: di-tert-butylphosphine;6-(chloromethyl)-2,2’-bipyridine in methanol at 50; for 48 h;Inert atmosphere;
Stage #2: with triethylamine in methanol at 20; for 1 h;Inert atmosphere;
References:
Balaraman, Ekambaram;Gnanaprakasam, Boopathy;Shimon, Linda J. W.;Milstein, David [Journal of the American Chemical Society,2010,vol. 132,# 47,p. 16756 - 16758] Location in patent:supporting information; experimental part