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6-(dimethylamino)-3,4-dihydroisoquinolin-1(2H)-one synthesis

10synthesis methods
Benzamide, 4-(dimethylamino)-N-[(dimethylamino)methylene]-2-methyl-

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6-(dimethylamino)-3,4-dihydroisoquinolin-1(2H)-one

1178884-33-7
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-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: potassium tert-butylate / tetrahydrofuran / 24 h / 60 °C
2: palladium on activated charcoal; hydrogen / ethanol

References:

Hong, Jun Bae;Davidson, James P.;Jin, Qingwu;Lee, Gary R.;Matchett, Michael;O'Brien, Erin;Welch, Michael;Bingenheimer, Bill;Sarma, Keshab [Organic Process Research and Development,2014,vol. 18,# 1,p. 228 - 238]