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ChemicalBook CAS DataBase List 6-ETHYLCHROMONE-2-CARBOXYLIC ACID

6-ETHYLCHROMONE-2-CARBOXYLIC ACID synthesis

1synthesis methods
-

Yield:-

Reaction Conditions:

Stage #1: 3-ethyl-6-hydroxyacetophenone;oxalic acid diethyl esterwith methanol;sodium methylate in 1,4-dioxane at 120; for 0.333333 h;Microwave irradiation;
Stage #2: with hydrogenchloride in 1,4-dioxane at 120; for 0.666667 h;Microwave irradiation;

References:

Angeli, Andrea;Kartsev, Victor;Petrou, Anthi;Pinteala, Mariana;Brovarets, Volodymyr;Slyvchuk, Sergii;Pilyo, Stepan;Geronikaki, Athina;Supuran, Claudiu T. [International Journal of Molecular Sciences,2021,vol. 22,# 10]

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