6-fluoro-2,3-diMethoxybenzoic acid synthesis
- Product Name:6-fluoro-2,3-diMethoxybenzoic acid
- CAS Number:265670-72-2
- Molecular formula:C9H9FO4
- Molecular Weight:200.16
124-38-9
121 suppliers
$214.00/14L
398-62-9
154 suppliers
$10.00/1g
265670-72-2
48 suppliers
$49.00/100mg
Yield:265670-72-2 64%
Reaction Conditions:
Stage #1: 4-fluoroveratrolewith lithium diisopropyl amide in tetrahydrofuran;hexane at -60; for 1 h;
Stage #2: carbon dioxide in tetrahydrofuran;hexane at -60; for 0.5 h;
References:
Plé, Patrick A.;Green, Tim P.;Hennequin, Laurent F.;Curwen, Jon;Fennell, Michael;Allen, Jack;Lambert-Van Der Brempt, Christine;Costello, Gerard [Journal of Medicinal Chemistry,2004,vol. 47,# 4,p. 871 - 887]