6-methoxy-1,5-Naphthyridin-2(1H)-one synthesis

5synthesis methods

Product Name:6-methoxy-1,5-Naphthyridin-2(1H)-one
CAS Number:27017-64-7
Molecular formula:C9H8N2O2
Molecular Weight:176.17

141-32-2
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34392-85-3 Synthesis

34392-85-3
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27017-64-7
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Yield:27017-64-7 33.2%

Reaction Conditions:

with Isopropylbenzene;N-Methyldicyclohexylamine;palladium diacetate;tri tert-butylphosphoniumtetrafluoroborate at 150;

References:

Hameed P, Shahul;Patil, Vikas;Solapure, Suresh;Sharma, Umender;Madhavapeddi, Prashanti;Raichurkar, Anandkumar;Chinnapattu, Murugan;Manjrekar, Praveena;Shanbhag, Gajanan;Puttur, Jayashree;Shinde, Vikas;Menasinakai, Sreenivasaiah;Rudrapatana, Suresh;Achar, Vijayashree;Awasthy, Disha;Nandishaiah, Radha;Humnabadkar, Vaishali;Ghosh, Anirban;Narayan, Chandan;Ramya;Kaur, Parvinder;Sharma, Sreevalli;Werngren, Jim;Hoffner, Sven;Panduga, Vijender;Kumar, C. N. Naveen;Reddy, Jitendar;Kumar Kn, Mahesh;Ganguly, Samit;Bharath, Sowmya;Bheemarao, Ugarkar;Mukherjee, Kakoli;Arora, Uma;Gaonkar, Sheshagiri;Coulson, Michelle;Waterson, David;Sambandamurthy, Vasan K.;De Sousa, Sunita M. [Journal of Medicinal Chemistry,2014,vol. 57,# 11,p. 4889 - 4905] Location in patent:supporting information