ChemicalBook CAS DataBase List 6-Methylimidazo[1,2-a]pyrimidine-3-carboxylic acid

6-Methylimidazo[1,2-a]pyrimidine-3-carboxylic acid synthesis

2synthesis methods

Product Name:6-Methylimidazo[1,2-a]pyrimidine-3-carboxylic acid
CAS Number:1020035-04-4
Molecular formula:C8H7N3O2
Molecular Weight:177.16

Imidazo[1,2-a]pyrimidine-3-carboxylic acid, 6-methyl-, ethyl ester

1339175-99-3
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6-Methylimidazo[1,2-a]pyrimidine-3-carboxylic acid

1020035-04-4
29 suppliers
$90.00/100mg

Yield:1020035-04-4 66%

Reaction Conditions:

Stage #1: ethyl 6-methylimidazo[1,2-a]pyrimidine-3-carboxylatewith lithium hydroxide in tetrahydrofuran at 20;
Stage #2: with hydrogenchloride in tetrahydrofuran;water; pH=5;

References:

Linton, Angelica;Kang, Ping;Ornelas, Martha;Kephart, Susan;Hu, Qiyue;Pairish, Mason;Jiang, Ying;Guo, Chuangxing [Journal of Medicinal Chemistry,2011,vol. 54,# 21,p. 7705 - 7712] Location in patent:supporting information; experimental part

50840-23-8
115 suppliers
$60.00/100mg

1020035-04-4
29 suppliers
$90.00/100mg

References