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ChemicalBook CAS DataBase List 6’-(pyridin-4-yl)-3,4’:2’,4’’-terpyridine
887917-77-3

6’-(pyridin-4-yl)-3,4’:2’,4’’-terpyridine synthesis

4synthesis methods
-

Yield:887917-77-3 50%

Reaction Conditions:

with ammonium hydroxide;potassium hydroxide in ethanol at 20; for 12 h;

Steps:

Synthesis of 2,6-bis(4′-pyridyl)-4-(3′-pyridyl)pyridine, L1

4-acetyl-pyridine (11.9 g,98 mmol) was added to an ethanol (250 mL) solution of 3-pyridinecarboxaldehyde (5.20 g,49 mmol). This solution was stirred until complete dissolution. Then, KOH pellets (7.44 g,133 mmol) and aqueous NH3 (28%, 140 ml) were successively added. The color of thesolution turned yellow and gradually black. The reaction mixture was stirred for 12 hours atambient temperature. During the stirring, a precipitate was formed. The precipitate wasfiltered off and washed with water. Greenish white solid was obtained (7.62 g, 50% yield).

References:

Yoshida, Jun;Nishikiori, Shin-Ichi;Yuge, Hidetaka [Journal of Coordination Chemistry,2013,vol. 66,# 24,p. 4344 - 4354]