DELTA 9-TRANS 12-TRANS OCTADECADIENOIC ACID ETHYL ESTER synthesis
1synthesis methods
- Product Name:DELTA 9-TRANS 12-TRANS OCTADECADIENOIC ACID ETHYL ESTER
- CAS Number:6114-21-2
- Molecular formula:C20H36O2
- Molecular Weight:308.5
Yield:-
Reaction Conditions:
with potassium hydroxide at 60; for 0.333333 h;Molecular sieve;Inert atmosphere;
Steps:
Methyl linoleate (2 g) was incubated with anhydrous ethanol (20 ml), KOH (0.2 g), and 4 g of molecular sieves for 20 minutes at 60°C with stirring. The reaction mixture was neutralized acetic acid and the ethyl linoleate product was extracted with ethyl acetate. Ethyl linoleate was cyclopropanated as described above using the Simmons-Smith reaction to produce DCPLA-ethyl ester. All reactions were carried out under a nitrogen atmosphere
References:
WO2013/71282,2013,A1 Location in patent:Paragraph 0205