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2-(2-Oxo-1,2,3,4-Tetrahydroquinolin-3-Yl)Acetic Acid synthesis

1synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: LDA / tetrahydrofuran
2: TFA / Heating

References:

Molteni, Valentina;He, Xiaohui;Nabakka, Juliet;Yang, Kunyong;Kreusch, Andreas;Gordon, Perry;Bursulaya, Badry;Warner, Ian;Shin, Tanya;Biorac, Tanya;Ryder, Neil S.;Goldberg, Ron;Doughty, John;He, Yun [Bioorganic and Medicinal Chemistry Letters,2004,vol. 14,# 6,p. 1477 - 1481]