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ChemicalBook CAS DataBase List 1H-Pyrrolo[2,3-b]pyridine, 3-(1-piperazinylmethyl)-

1H-Pyrrolo[2,3-b]pyridine, 3-(1-piperazinylmethyl)- synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 95 percent / NaBH3CN; acetic acid / methanol / 18 h / 60 °C / pH 5
2: 65 percent / H2SO4 / methanol / 1 h / 60 °C

References:

Oh, Seung-Jun;Lee, Kyo Chul;Lee, Sang-Yoon;Ryu, Eun Kyoung;Saji, Hideo;Choe, Yearn Seong;Chi, Dae Yoon;Kim, Sang Eun;Lee, Jeewoo;Kim, Byung-Tae [Bioorganic and Medicinal Chemistry,2004,vol. 12,# 21,p. 5505 - 5513]