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1H-Benzimidazole-2-acetonitrile,alpha-(hydroxyimino)-(9CI) synthesis

3synthesis methods
4414-88-4 Synthesis
2-(Cyanomethyl)benzimidazole

4414-88-4
228 suppliers
$8.00/5g

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Yield:63823-75-6 87%

Reaction Conditions:

with glacial acetic acid;NaNO2 at 0 - 25; for 12 h;

References:

Van Der Westhuyzen, Renier;Mabhula, Amanda;Njaria, Paul M.;Müller, Rudolf;Ngumbu Muhunga, Denis;Taylor, Dale;Lawrence, Nina;Njoroge, Mathew;Brunschwig, Christel;Moosa, Atica;Singh, Vinayak;Rao, Srinivasa P.S.;Manjunatha, Ujjini H.;Smith, Paul W.;Warner, Digby F.;Street, Leslie J.;Chibale, Kelly [Journal of Medicinal Chemistry,2021,vol. 64,# 13,p. 9444 - 9457] Location in patent:supporting information