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ChemicalBook CAS DataBase List 2-AMino-6-chloro-9-[(2,3,5-tri-O-benzoyl- 2-C-Methyl-β-D-ribofuranosyl)]-9H-purine

2-AMino-6-chloro-9-[(2,3,5-tri-O-benzoyl- 2-C-Methyl-β-D-ribofuranosyl)]-9H-purine synthesis

5synthesis methods
-

Yield:641571-44-0 92%

Reaction Conditions:

with trimethylsilyl trifluoromethanesulfonate;1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile at -40 - 80; for 5 h;

References:

Zhou, Longhu;Zhang, Hongwang;Tao, Sijia;Ehteshami, Maryam;Cho, Jong Hyun;McBrayer, Tamara R.;Tharnish, Philip;Whitaker, Tony;Amblard, Franck;Coats, Steven J.;Schinazi, Raymond F. [ACS Medicinal Chemistry Letters,2016,vol. 7,# 1,p. 17 - 22] Location in patent:supporting information