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ChemicalBook CAS DataBase List Trimethylsilylketene Ethyl Trimethylsilyl Acetal (mixture of isomers)
65946-56-7

Trimethylsilylketene Ethyl Trimethylsilyl Acetal (mixture of isomers) synthesis

3synthesis methods
-

Yield:65946-56-7 93%

Reaction Conditions:

Stage #1: trimethylsilanyl-acetic acid ethyl esterwith lithium diisopropyl amide in tetrahydrofuran at -78;
Stage #2: tert-butyldimethylsilyl chloride in tetrahydrofuran at -78;Further stages.;

References:

Michida, Makoto;Mukaiyama, Teruaki [Chemistry Letters,2008,vol. 37,# 7,p. 704 - 705]

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